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By Scott A., Prof. Snyder,Marco Bella,Alexander Dömling,Jon Boyce,Gaelle Blond,Iain Coldham

The fast speed of evolution in domino, or cascade-based ameliorations has revolutionized the perform of chemical synthesis for the production of normal items, designed molecules, and pharmaceuticals.


"Science of Synthesis: functions of Domino differences in natural Synthesis" explores the subject completely and systematically, serving because the foundation for functional purposes and destiny examine. The 2-volume set offers the state of the art when it comes to layout, technique, and experimental strategies, resulting in a number of occasions being finished inside of a unmarried response vessel. The content material is geared up through the middle form of response used to start up the development, be it a pericyclic response, a metal-mediated transformation, radical chemistry, or an acid-induced cascade between many others.


Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.

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